MersV1, France, Analysis, bibRecord, 000108

Heat inactivation of the Middle East respiratory syndrome coronavirus

Identifieur interne : 000108 ( France/Analysis ); précédent : 000107; suivant : 000109

Heat inactivation of the Middle East respiratory syndrome coronavirus

Auteurs : India Leclercq [France] ; Christophe Batéjat [France] ; Ana M. Burguière [France] ; Jean-Claude Manuguerra [France]

Source :

Influenza and Other Respiratory Viruses [ 1750-2640 ] ; 2014.

RBID : PMC:4181824

Descripteurs français

KwdFr :
- Coronavirus du syndrome respiratoire du Moyen-Orient (), Coronavirus du syndrome respiratoire du Moyen-Orient (physiologie), Désinfection (), Humains, Infections à coronavirus (virologie), Température élevée.
MESH :
- physiologie : Coronavirus du syndrome respiratoire du Moyen-Orient.
- virologie : Infections à coronavirus.
- Coronavirus du syndrome respiratoire du Moyen-Orient, Désinfection, Humains, Température élevée.

English descriptors

KwdEn :
- Coronavirus Infections (virology), Disinfection (methods), Hot Temperature, Humans, Middle East Respiratory Syndrome Coronavirus (chemistry), Middle East Respiratory Syndrome Coronavirus (physiology).
MESH :
- chemistry : Middle East Respiratory Syndrome Coronavirus.
- methods : Disinfection.
- physiology : Middle East Respiratory Syndrome Coronavirus.
- virology : Coronavirus Infections.
- Hot Temperature, Humans.

Abstract

The culture supernatants of the emerging Middle East respiratory syndrome coronavirus (MERS-CoV) were submitted to three temperatures over time and tested for infectivity by TCID₅₀ method on Vero E6 cells. At 56°C, almost 25 minutes were necessary to reduce the initial titre by 4 log₁₀. Increasing temperature to 65°C had a strong negative effect on viral infectivity as virucidy dropped significantly to 1 minute. On the contrary, no significant decrease in titre was observed after 2 hours at 25°C. These data might be useful in establishing biosafety measures in laboratories against MERS-CoV.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181824

DOI: 10.1111/irv.12261
PubMed: 25074677
PubMed Central: 4181824

Affiliations:

France

Links to Exploration step

PMC:4181824

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p>The culture supernatants of the emerging Middle East respiratory syndrome coronavirus (MERS-CoV) were submitted to three temperatures over time and tested for infectivity by TCID<sub>50</sub>
 method on Vero E6 cells. At 56°C, almost 25 minutes were necessary to reduce the initial titre by 4 log<sub>10</sub>
. Increasing temperature to 65°C had a strong negative effect on viral infectivity as virucidy dropped significantly to 1 minute. On the contrary, no significant decrease in titre was observed after 2 hours at 25°C. These data might be useful in establishing biosafety measures in laboratories against MERS-CoV.</p>
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Serveur d'exploration MERS

Heat inactivation of the Middle East respiratory syndrome coronavirus

Heat inactivation of the Middle East respiratory syndrome coronavirus

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration MERS
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